SCHEMBL8102083

SCHEMBL8102083

CCc1cc(Cl)c(N)cc1O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.44
BACE1 P56817 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
SLC9A1 P19634 1/20 0.38
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
NPC1 O15118 1/20 0.36
HSP90AA1 P07900 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13767807 0.82 HPGD (0.48) BACE1ESR1ESR2HSP90AA1ALOX15
SCHEMBL28766936 0.81 TYR (0.49) GAANPC1ALOX15ALDH1A1CYP3A4
SCHEMBL10948580 0.80 GAA (0.57) GAACA12CA1CA2CA7
SCHEMBL70471 0.80 HSD17B10 (0.46) GAABACE1ESR1ESR2HSP90AA1
SCHEMBL16736856 0.80 ALOX15 (0.47) GAABACE1ESR1ESR2HSP90AA1
SCHEMBL5320973 0.77 BACE1 (0.44) BACE1ESR1ESR2ALOX15ALOX12
SCHEMBL574139 0.77 LMNA (0.48) GAABACE1CA12CA1CA2
SCHEMBL14753729 0.77 CD44 (0.48) GAASLC9A1NPC1ALOX15ALDH1A1
SCHEMBL1426074 0.76 GAA (0.50) GAACA12CA1CA2CA7
SCHEMBL31163154 0.76 GAA (0.50) GAACA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0971681-A1 MEANS AND METHOD FOR DYING AND COLORING KERATIN FIBERS Hans Schwarzkopf GmbH & Co. KG (DE) 2000-01-19 EP disclosed
EP-0966449-A1 NOVEL 1,4-DIAZACYCLOHEPTANE DERIVATIVES AND THEIR USE IN HAIR OXIDATION DYES Henkel Kommanditgesellschaft auf Aktien (DE) 1999-12-29 EP disclosed
WO-1998038976-A1 MEANS AND METHOD FOR DYING AND COLORING KERATIN FIBERS HANS SCHWARZKOPF GMBH & CO. KG (DE) 1998-09-11 WO disclosed
WO-1998038175-A1 NOVEL 1,4-DIAZACYCLOHEPTANE DERIVATIVES AND THEIR USE IN HAIR OXIDATION DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-09-03 WO disclosed