Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532886 | 0.86 | KIF11 (0.50) | KIF11DAORAB9APTGESCYP2C9 | |
| SCHEMBL27410225 | 0.82 | DAO (0.49) | KIF11DAORAB9APTGESCYP2C9 | |
| SCHEMBL27409224 | 0.80 | KIF11 (0.44) | KIF11DAORAB9APTGESCYP2C9 | |
| SCHEMBL27388577 | 0.78 | PTGS2 (0.53) | KIF11DAORAB9AHSD17B10TSHR | |
| SCHEMBL27420343 | 0.78 | KDM4E (0.46) | KIF11DAORAB9APTGESCYP2C9 | |
| SCHEMBL9308632 | 0.77 | KDM4E (0.47) | KIF11DAORAB9APTGESCYP2C9 | |
| SCHEMBL9312351 | 0.76 | DAO (0.44) | KIF11DAORAB9APTGESCYP2C9 | |
| SCHEMBL9308464 | 0.75 | KDM4E (0.45) | KIF11DAORAB9AHSD17B10TSHR | |
| SCHEMBL9308787 | 0.75 | PARP1 (0.48) | KIF11DAORAB9AHSD17B10TSHR | |
| SCHEMBL27410857 | 0.75 | DAO (0.43) | KIF11DAORAB9APTGESCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1077192-A | The 2-oxoquinoline derivatives | MERCK PATENT GMBH (DE) | 1993-10-13 | — | — | CN | disclosed |