Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27414302 | 0.83 | TSHR (0.50) | — | |
| Pyrazine SCHEMBL27788487 | 0.79 | KDM4E (0.33) | — | |
| Pyrimidine SCHEMBL3705061 | 0.79 | — | — | |
| Pyrimidine SCHEMBL22983946 | 0.78 | HDAC1 (0.31) | — | |
| Benzene SCHEMBL27560754 | 0.75 | ALDH1A1 (0.38) | — | |
| Pyrimidine SCHEMBL3163212 | 0.73 | — | — | |
| Pyrimidine SCHEMBL3709916 | 0.73 | — | — | |
| Pyrimidine SCHEMBL27891987 | 0.73 | — | — | |
| Benzene SCHEMBL27456300 | 0.72 | ALDH1A1 (0.36) | — | |
| Pyrimidine SCHEMBL6837713 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056755-B | Five-ring heterocycles amides WNT pathway inhibitor | 苏州信诺维医药科技有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-107382877-A | A kind of synthetic method of 4 amino 2 methyl 5 (bromomethyl) pyrimidine hydrobromate | 成都百事兴科技实业有限公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-107056755-A | Five-ring heterocycles amide-type WNT pathway inhibitors | 杭州雷索药业有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-1103770-C | Quinoxalinediones | PFIZER RES AND DEV CO N V S A (IE) | 2003-03-26 | — | — | CN | disclosed |
| CN-1213369-A | Quinoxalinedione compound | PFIZER RES & DEV (IE) | 1999-04-07 | — | — | CN | disclosed |