Pyrimidine

Pyrimidine

SCHEMBL3709916

CC=O.c1cncnc1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL3705061 0.80
Pyrimidine SCHEMBL3163212 0.80
Pyrimidine SCHEMBL27891987 0.80
Pyridine SCHEMBL5969174 0.80
Pyrimidine SCHEMBL27828571 0.79 ALDH1A1 (0.30)
Pyrimidine SCHEMBL27755630 0.78
Pyrimidine SCHEMBL10646 0.78 TSHR (0.50)
Pyrimidine SCHEMBL19437633 0.78 TSHR (0.50)
Pyrimidine SCHEMBL1846 0.78
Pyrimidine SCHEMBL2218253 0.75 TSHR (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9981940-B2 Aryl sulfide derivatives and aryl sulfoxide derivatives as acaricides and insecticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-05-29 US disclosed
US-9783509-B2 Six-membered C-N-linked aryl sulfide derivatives and aryl sulfoxide derivatives as pest conrol agents BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-10-10 US disclosed
US-20160251321-A1 SIX-MEMBERED C-N-LINKED ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE ERIVATVES AS PEST CONROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-09-01 US disclosed
US-20160145235-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-26 US disclosed
US-20160130240-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-12 US disclosed
US-7741485-B2 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds BASF AKTIENGESELLSCHAFT (DE) 2010-06-22 US disclosed
US-20060211577-A1 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds BASF AKTIENGESELLSCHAFT (DE) 2006-09-21 US disclosed
US-5877121-A HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1999-03-02 US disclosed
US-5877121-A HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1999-03-02 US disclosed
US-5877121-A HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1999-03-02 US disclosed