Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.36 |
| ▸ | POLRMT | O00411 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27412797 | 0.89 | TMPRSS2 (0.51) | TMPRSS2P2RX3P2RX2P2RY2P2RY1 | |
| SCHEMBL27412879 | 0.88 | TMPRSS2 (0.51) | TMPRSS2P2RX3P2RX2P2RY2P2RY1 | |
| SCHEMBL30973763 | 0.88 | TMPRSS2 (0.49) | TMPRSS2P2RX3P2RX2P2RY2P2RY1 | |
| SCHEMBL25821576 | 0.87 | TMPRSS2 (0.51) | TMPRSS2P2RX3P2RX2P2RY2P2RY1 | |
| SCHEMBL27412794 | 0.87 | TMPRSS2 (0.51) | TMPRSS2P2RX3P2RX2P2RY2P2RY1 | |
| SCHEMBL30973767 | 0.87 | TMPRSS2 (0.52) | TMPRSS2P2RX3P2RX2P2RY2P2RY1 | |
| SCHEMBL27412881 | 0.85 | TMPRSS2 (0.47) | TMPRSS2P2RX3P2RX2P2RY2P2RY1 | |
| SCHEMBL30973741 | 0.84 | TMPRSS2 (0.66) | TMPRSS2 | |
| Rdv-Tp SCHEMBL24492746 | 0.83 | POLRMT (0.51) | TMPRSS2P2RX3P2RX2P2RY1P2RX4 | |
| Rdv-Tp SCHEMBL10120881 | 0.83 | POLRMT (0.51) | TMPRSS2P2RX3P2RX2P2RY1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129963-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024129963-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |