SCHEMBL25821576

SCHEMBL25821576

N#C[C@@]1(c2ccc3c(NO)ncnn23)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.79

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.51
▸ P2RX3 P56373 3/20 0.39
▸ P2RX2 Q9UBL9 3/20 0.39
▸ POLRMT O00411 1/20 0.39
▸ P2RX4 Q99571 1/20 0.39
▸ GPR17 Q13304 2/20 0.37
▸ NT5E P21589 1/20 0.37
▸ P2RY2 P41231 3/20 0.36
▸ P2RY1 P47900 1/20 0.36
▸ P2RY6 Q15077 1/20 0.36
▸ P2RY12 Q9H244 1/20 0.36
▸ P2RY4 P51582 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rdv-Tp SCHEMBL24492746 0.89 POLRMT (0.51) TMPRSS2P2RX3P2RX2POLRMTP2RX4
Rdv-Tp SCHEMBL23278555 0.89 POLRMT (0.51) TMPRSS2P2RX3P2RX2POLRMTP2RX4
Rdv-Tp SCHEMBL10120881 0.89 POLRMT (0.51) TMPRSS2P2RX3P2RX2POLRMTP2RX4
Rdv-Tp SCHEMBL24492745 0.89 POLRMT (0.51) TMPRSS2P2RX3P2RX2POLRMTP2RX4
Rdv-Tp SCHEMBL26003192 0.89 POLRMT (0.51) TMPRSS2P2RX3P2RX2POLRMTP2RX4
SCHEMBL27412879 0.88 TMPRSS2 (0.51) TMPRSS2P2RX3P2RX2POLRMTP2RX4
SCHEMBL27412878 0.87 TMPRSS2 (0.51) TMPRSS2P2RX3P2RX2POLRMTP2RX4
SCHEMBL27412797 0.87 TMPRSS2 (0.51) TMPRSS2P2RX3P2RX2POLRMTP2RX4
SCHEMBL27412794 0.87 TMPRSS2 (0.51) TMPRSS2P2RX3P2RX2POLRMTP2RX4
SCHEMBL30973767 0.87 TMPRSS2 (0.52) TMPRSS2P2RX3P2RX2POLRMTP2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG VIGONVITA LIFE SCIENCES CO., LTD. (CN) 2023-07-13 — — US disclosed
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG VIGONVITA LIFE SCIENCES CO., LTD. (CN) 2023-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG PNP, TYMP, PIGS TMPRSS2 145/4885P2RX3 86/4885P2RX2 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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