Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24753973 | 0.82 | ALDH1A1 (0.51) | LMNAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL733377 | 0.80 | MEN1 (0.47) | LMNATP53MAPTKMT2AALDH1A1 | |
| SCHEMBL25113406 | 0.77 | OGA (0.46) | MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL31198823 | 0.74 | ALDH1A1 (0.43) | LMNATP53MAPTKMT2AALDH1A1 | |
| SCHEMBL22544256 | 0.70 | GCKR (0.36) | TP53KDM4E | |
| SCHEMBL2333525 | 0.70 | KDM4E (0.49) | LMNATP53MAPTALDH1A1NPC1 | |
| SCHEMBL28427402 | 0.69 | HRH3 (0.45) | LMNATP53MAPTKMT2AALDH1A1 | |
| SCHEMBL3588853 | 0.68 | POLB (0.49) | LMNAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL347328 | 0.68 | CYP1A2 (0.51) | LMNAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL22544223 | 0.68 | MAPT (0.63) | MAPTKMT2AMEN1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050370-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-03-07 | — | — | WO | disclosed |