Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743954 | 0.92 | TRIM24 (0.35) | ALDH1A1HTT | |
| SCHEMBL27676352 | 0.86 | ERN1 (0.34) | — | |
| SCHEMBL13887602 | 0.84 | MAOA (0.35) | MAOAMAOBALDH1A1HTT | |
| SCHEMBL28131959 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2422131 | 0.76 | HSD17B10 (0.50) | ALDH1A1 | |
| SCHEMBL28176949 | 0.75 | — | — | |
| SCHEMBL11427988 | 0.74 | HSD17B10 (0.48) | ALDH1A1 | |
| SCHEMBL17504448 | 0.74 | KDM4E (0.54) | ALDH1A1 | |
| SCHEMBL28191969 | 0.74 | MAPT (0.34) | ALDH1A1HTT | |
| SCHEMBL9693848 | 0.74 | HSD17B10 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108456183-A | The preparation method and intermediate of Gedatolisib | 上海工程技术大学 | 2018-08-28 | — | — | CN | claimed |
| CN-109790146-A | Medical compounds | 阿尔麦克探索有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-106083899-B | Condensed heterocyclic derivates and application method | 安姆根有限公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-108659005-A | Quinazoline derivatives as EGFR inhibitors | 南京明德新药研发股份有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-108640928-A | Quinazoline compounds as EGFR inhibitor | 南京明德新药研发股份有限公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-104860924-B | Melanocortin-4 receptor modulators prepare their method and its purposes in human medicine and cosmetics | 盖尔德马研究及发展公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-104876923-B | Heteroaryl piperidine and heteroaryl based piperazine derivative as fungicide | 拜耳知识产权有限责任公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-108473426-A | Cyclic amine derivatives and its medical usage | 东丽株式会社 | 2018-08-31 | — | — | CN | disclosed |
| CN-108456183-A | The preparation method and intermediate of Gedatolisib | 上海工程技术大学 | 2018-08-28 | — | — | CN | disclosed |
| CN-106459002-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-101268077-A | Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators | ASTRAZENECA AB (SE) | 2008-09-17 | — | — | CN | disclosed |
| CN-1229343-C | Novel compounds | ASTRAZENECA AB (SE) | 2005-11-30 | — | — | CN | disclosed |
| CN-1501915-A | Bipiperidine derivatives and their use as chemokine receptor inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | disclosed |
| CN-1426393-A | Novel compounds | ASTRAZENECA AB (SE) | 2003-06-25 | — | — | CN | disclosed |
| CN-1098838-C | Substituted N- (indole-2-carbonyl) -beta-alaninamides and derivatives as antidiabetics | PFIZER (US) | 2003-01-15 | — | — | CN | disclosed |
| CN-1374082-A | Use of glycogen sulphofoenzyme inhibitor | PFIZER (US) | 2002-10-16 | — | — | CN | disclosed |
| CN-1351497-A | Aminopyrimidines as sorbitol dehydrogenase inhibitors | PFIZER PROD INC (US) | 2002-05-29 | — | — | CN | disclosed |
| CN-1281433-A | Hydroxamic acid derivatives as matrix metalloproteinase (MMP) inhibitors | PFIZER LTD (US) | 2001-01-24 | — | — | CN | disclosed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | disclosed |
| CN-1140709-A | Substituted N- (indole-2-carbonyl) -beta-alaninamides and derivatives as antidiabetics | PFIZER (US) | 1997-01-22 | — | — | CN | disclosed |