Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012942 | 0.86 | MEN1 (0.56) | TYMSALDH1A1RAB9ANPC1HSP90AA1 | |
| SCHEMBL30572637 | 0.79 | AAK1 (0.58) | ALDH1A1RAB9ANPC1HSP90AA1ESR2 | |
| SCHEMBL16809191 | 0.78 | ALDH1A1 (0.58) | TYMSALDH1A1RAB9ANPC1HSP90AA1 | |
| SCHEMBL7808593 | 0.78 | TDP1 (0.54) | TYMSRAB9ANPC1TDP1MAPT | |
| SCHEMBL7813664 | 0.77 | RAB9A (0.51) | ALDH1A1RAB9ANPC1MAPTGAA | |
| Hydrochloric Acid SCHEMBL8480485 | 0.77 | TDP1 (0.52) | TYMSRAB9ANPC1TDP1MAPT | |
| Hydrochloric Acid SCHEMBL8478189 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1RAB9ANPC1MAPTGAA | |
| Hydrochloric Acid SCHEMBL7085899 | 0.76 | TYMS (0.46) | TYMSALDH1A1RAB9ANPC1HSP90AA1 | |
| SCHEMBL26039239 | 0.74 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1HSP90AA1ESR2 | |
| SCHEMBL7808670 | 0.74 | RAB9A (0.51) | ALDH1A1RAB9ANPC1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090620-C | New benzimidazole, benzoxazole and benzothiazole compounds, process for preparing them and pharmaceutical compositions containing them | SEUER LAB (FR) | 2002-09-11 | — | — | CN | disclosed |
| CN-1174192-A | New benzimidazole, benzoxazole and benzothiazole compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-02-25 | — | — | CN | disclosed |