Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31302989 | 0.87 | L3MBTL1 (0.64) | SMN1; SMN2KMT2AHPGDMEN1POLB | |
| SCHEMBL2777259 | 0.87 | L3MBTL1 (0.64) | SMN1; SMN2KMT2AHPGDMEN1POLB | |
| Hydrochloric Acid SCHEMBL2777750 | 0.86 | L3MBTL1 (0.62) | SMN1; SMN2KMT2AHPGDMEN1POLB | |
| SCHEMBL826321 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AHPGDMEN1DRD2 | |
| SCHEMBL12908000 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AHPGDMEN1POLB | |
| SCHEMBL8278944 | 0.81 | KMT2A (0.60) | SMN1; SMN2KMT2AHPGDMEN1POLB | |
| SCHEMBL5834552 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2AHPGDMEN1POLB | |
| SCHEMBL13450150 | 0.80 | PPARA (0.59) | SMN1; SMN2KMT2AHPGDMEN1DRD2 | |
| SCHEMBL10102862 | 0.80 | PPARA (0.59) | SMN1; SMN2KMT2AHPGDMEN1DRD2 | |
| SCHEMBL20230314 | 0.80 | PPARA (0.59) | SMN1; SMN2KMT2AHPGDMEN1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1092659-C | Novel pyrimidine derivative | OTSUKA PHARMA CO LTD (JP) | 2002-10-16 | — | — | CN | disclosed |
| CN-1250450-A | Novel pyrimidine derivative | OTSUKA PHARMA CO LTD (JP) | 2000-04-12 | — | — | CN | disclosed |