Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27415015 | 1.00 | HPGD (0.33) | HPGDSMN1; SMN2HTTOPRD1ABCB11 | |
| SCHEMBL27415042 | 1.00 | HPGD (0.33) | HPGDSMN1; SMN2HTTOPRD1ABCB11 | |
| SCHEMBL27415032 | 1.00 | HPGD (0.33) | HPGDSMN1; SMN2HTTOPRD1ABCB11 | |
| SCHEMBL27415036 | 0.95 | HPGD (0.36) | HPGDSMN1; SMN2HTTOPRD1ABCB11 | |
| SCHEMBL27276995 | 0.90 | OPRD1 (0.34) | HPGDSMN1; SMN2HTTOPRD1ABCB11 | |
| SCHEMBL27277097 | 0.90 | OPRD1 (0.34) | HPGDSMN1; SMN2HTTOPRD1ABCB11 | |
| SCHEMBL27332881 | 0.90 | OPRD1 (0.34) | HPGDSMN1; SMN2HTTOPRD1ABCB11 | |
| SCHEMBL27415022 | 0.88 | HPGD (0.33) | HPGDSMN1; SMN2HTTOPRD1ABCB11 | |
| SCHEMBL27333244 | 0.81 | OPRM1 (0.33) | HPGDSMN1; SMN2HTTOPRD1OPRM1 | |
| SCHEMBL27415010 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137502-A2 | PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-06-27 | — | — | WO | disclosed |