Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101018 | 0.83 | CA2 (0.62) | CA2CA4CA5ATSHRANPEP | |
| SCHEMBL342876 | 0.80 | ENPP2 (0.58) | CA2S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL12611089 | 0.78 | ENPP2 (0.66) | S1PR2S1PR4S1PR1S1PR3SLC6A3 | |
| SCHEMBL9069707 | 0.78 | HTR2A (0.75) | HDAC8HTR2AHDAC1HDAC3HDAC4 | |
| SCHEMBL877356 | 0.77 | ENPP2 (0.69) | HTR2AS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL28629026 | 0.77 | ENPP2 (0.69) | HTR2AS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL4306211 | 0.77 | ENPP2 (0.69) | HTR2AS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL1100803 | 0.77 | ENPP2 (0.69) | HTR2AS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL4237288 | 0.77 | ENPP2 (0.69) | HTR2AS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL1100868 | 0.77 | ENPP2 (0.69) | HTR2AS1PR2S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089614-A | Alpha-phosphonosulfonate squalene synthetase inhibitors and method | SQUIBB & SONS INC (US) | 1994-07-20 | — | — | CN | disclosed |