⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664910 | 0.67 | — | — | |
| SCHEMBL9373386 | 0.67 | — | — | |
| SCHEMBL21597560 | 0.65 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL27415137 | 0.63 | — | — | |
| SCHEMBL9865789 | 0.62 | — | — | |
| SCHEMBL27415135 | 0.62 | HPGD (0.37) | — | |
| SCHEMBL27415141 | 0.61 | — | — | |
| SCHEMBL21603894 | 0.61 | KDM4E (0.35) | — | |
| SCHEMBL21603995 | 0.60 | P2RX7 (0.35) | — | |
| SCHEMBL27157223 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |