Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176639 | 0.82 | SCN8A (0.45) | CTSATSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28308744 | 0.81 | KDM4E (0.51) | GAAMGAMSIMGAM2RAB9A | |
| SCHEMBL29869241 | 0.80 | IKBKB (0.43) | IKBKBGAARAB9ASMN1; SMN2TP53 | |
| SCHEMBL7832536 | 0.78 | CTSA (0.36) | CTSASMN1; SMN2TLR8KDM4EMAPK1 | |
| SCHEMBL17194888 | 0.77 | CLK4 (0.43) | CTSATSHRGAARAB9ASMN1; SMN2 | |
| SCHEMBL13000747 | 0.76 | ALDH1A1 (0.44) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL17194883 | 0.76 | CCNT1 (0.43) | CTSAMEN1KMT2ATEKTLR8 | |
| SCHEMBL2782878 | 0.76 | CTSA (0.44) | IKBKBCTSAGAARAB9ASMN1; SMN2 | |
| SCHEMBL1423554 | 0.76 | SQOR (0.46) | IKBKBTSHRRAB9ANPC1MEN1 | |
| SCHEMBL8503115 | 0.76 | CA1 (0.51) | IKBKBRAB9ASMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137548-A2 | INHIBITORS OF JAK2 | Llydaw Therapeutics, Inc. (US) | 2024-06-27 | — | — | WO | disclosed |