Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 7/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 3/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11084509 | 0.74 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL20594635 | 0.71 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL27340789 | 0.70 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL11087997 | 0.69 | KDM4E (0.43) | KDM4ETOP2ATOP2B | |
| SCHEMBL144485 | 0.69 | TOP2A (0.46) | TOP2ATOP2BPOLB | |
| Bicarbonate SCHEMBL9047917 | 0.69 | TOP2A (0.58) | TOP2ATOP2B | |
| SCHEMBL7998227 | 0.68 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL21056698 | 0.68 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL27339827 | 0.68 | TOP2A (0.58) | KDM4EHSD17B10ALDH1A1HPGDTOP2A | |
| SCHEMBL11869374 | 0.67 | CHRM1 (0.45) | KDM4EALDH1A1NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1087634-A | 7-Isoindolinyl-quinolone derivatives and 7-isoindolinyl-naphthyridone derivatives | BAYER AG (DE) | 1994-06-08 | — | — | CN | disclosed |