Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953880 | 0.91 | LMNA (0.42) | LMNAMAPTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL548527 | 0.89 | MEN1 (0.42) | LMNAMAPTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL27448235 | 0.82 | MEN1 (0.44) | MAPTCYP1A2CYP2D6CYP3A4ALOX15 | |
| SCHEMBL549599 | 0.82 | IKBKB (0.45) | MAPTCYP3A4ALOX15TP53KMT2A | |
| SCHEMBL27417752 | 0.81 | MEN1 (0.39) | LMNAMAPTCYP3A4ALOX15TP53 | |
| SCHEMBL549463 | 0.81 | MEN1 (0.41) | MAPTCYP3A4ALOX15TP53KMT2A | |
| SCHEMBL549772 | 0.78 | MEN1 (0.44) | MAPTCYP3A4ALOX15TP53KMT2A | |
| SCHEMBL548910 | 0.76 | CA1 (0.34) | LMNACYP1A2CYP3A4HIF1AKMT2A | |
| SCHEMBL548704 | 0.76 | MEN1 (0.34) | LMNAMAPTCYP1A2CYP3A4ALOX15 | |
| SCHEMBL2089503 | 0.76 | MEN1 (0.32) | KMT2AMEN1GAAPOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101547885-A | Adamantane derivative, process for producing the same, and resin composition containing adamantane derivative | IDEMITSU KOSAN CO (JP) | 2009-09-30 | — | — | CN | disclosed |
| CN-1117966-A | Biphenyl derivatives | EISAI CO LTD (JP) | 1996-03-06 | — | — | CN | disclosed |