SCHEMBL2089503

SCHEMBL2089503

Cc1cc(C(c2cc(C)c(O)cc2C)c2cc(C34CC5CC(C3)CC(c3cc(C(c6cc(C)c(O)cc6C)c6cc(C)c(O)cc6C)c(O)cc3C)(C5)C4)c(C)cc2O)c(C)cc1O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
GFER P55789 1/20 0.32
KMT2A Q03164 1/20 0.32
IL1B P01584 1/20 0.32
IKBKB O14920 1/20 0.31
RARA P10276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4607854 0.85 KMT2A (0.39) MEN1POLBGAAGFERKMT2A
SCHEMBL4953880 0.85 LMNA (0.42) MEN1POLBGAAGFERKMT2A
SCHEMBL4954586 0.82 MEN1 (0.46) MEN1POLBGAAGFERKMT2A
SCHEMBL4953194 0.81
SCHEMBL4949937 0.79 MEN1 (0.33) MEN1POLBGAAGFERKMT2A
SCHEMBL4950312 0.77 POLB (0.32) MEN1POLBGAAGFERKMT2A
SCHEMBL27448235 0.76 MEN1 (0.44) MEN1POLBGAAGFERKMT2A
SCHEMBL6760923 0.76 ALDH1A1 (0.39) MEN1POLBGAAGFERKMT2A
SCHEMBL27416248 0.76 LMNA (0.45) MEN1POLBGAAGFERKMT2A
SCHEMBL4955968 0.74 PGR (0.33) MEN1POLBGAAGFERKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7862981-B2 Compound, positive resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2011-01-04 US disclosed
US-20100009284-A1 COMPOUND, POSITIVE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2010-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100009284-A1 COMPOUND, POSITIVE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN MRPS27, PSMC2, PSMD7 MEN1 3250/4885POLB 296/4885GAA 2709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.