Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | F2R | P25116 | 8/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470058 | 0.87 | MAPT (0.56) | MAPTGAAF2RHDAC3HDAC4 | |
| SCHEMBL14351016 | 0.86 | MAPT (0.58) | MAPTGAAF2RHDAC3HDAC4 | |
| SCHEMBL24538415 | 0.86 | MAPT (0.75) | MAPTGAAF2RHDAC3HDAC4 | |
| SCHEMBL12255382 | 0.84 | MTNR1B (0.56) | MAPTGAAF2RHDAC3HDAC4 | |
| SCHEMBL11202642 | 0.84 | MAPT (0.53) | MAPTGAAF2RHDAC3HDAC4 | |
| SCHEMBL11202648 | 0.84 | MAPT (0.53) | MAPTGAAF2RHDAC3HDAC4 | |
| SCHEMBL10975643 | 0.84 | F2R (0.73) | MAPTF2RMTNR1BALDH1A1HPGD | |
| SCHEMBL4599428 | 0.83 | MAPT (0.58) | MAPTGAAF2RHDAC3HDAC4 | |
| SCHEMBL15946032 | 0.82 | HDAC3 (0.63) | MAPTGAAHDAC3HDAC4HDAC1 | |
| SCHEMBL25016092 | 0.82 | MAPT (0.57) | MAPTGAAF2RHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |