Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HRH1 | P35367 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3750772 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1HTR2AHRH1TDP1 | |
| SCHEMBL28848778 | 0.75 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNACHRNB2CHRNB4 | |
| SCHEMBL28101931 | 0.68 | ALOX5 (0.43) | KDM4EALDH1A1HTR2AHRH1TDP1 | |
| SCHEMBL1870280 | 0.67 | — | — | |
| SCHEMBL316110 | 0.67 | — | — | |
| SCHEMBL42818 | 0.67 | — | — | |
| SCHEMBL27294646 | 0.66 | HTT (0.43) | KDM4EALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL28147710 | 0.65 | MIF (0.44) | KDM4EALDH1A1HTR2AHRH1TDP1 | |
| Hydrochloric Acid SCHEMBL10398523 | 0.65 | TDP1 (0.48) | KDM4EALDH1A1HTR2AHRH1TDP1 | |
| SCHEMBL27418689 | 0.65 | MIF (0.44) | KDM4EALDH1A1HTR2AHRH1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093701-A | Antiretroviral hydrazine derivative | CIBA GEIGY AG (CH) | 1994-10-19 | — | — | CN | disclosed |