SCHEMBL27417217

SCHEMBL27417217

CC(C)C(=O)O.O=[N+]([O-])c1ccc2[nH]cnc2c1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.60
NAMPT P43490 1/20 0.60
XDH P47989 1/20 0.60
ALDH1A1 P00352 4/20 0.48
PARP1 P09874 1/20 0.48
KDM4E B2RXH2 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
MAPT P10636 4/20 0.43
GAA P10253 1/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
NPY1R P25929 1/20 0.43
NPY2R P49146 1/20 0.43
PTPRA P18433 1/20 0.43
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28050837 0.90 CYP3A4 (0.65) CYP3A4NAMPTXDHALDH1A1PARP1
SCHEMBL271340 0.87 CYP3A4 (0.77) CYP3A4NAMPTXDHALDH1A1PARP1
SCHEMBL29923659 0.87 CYP3A4 (0.77) CYP3A4NAMPTXDHALDH1A1PARP1
Nitric Acid SCHEMBL4907401 0.86 CYP3A4 (0.71) CYP3A4NAMPTXDHALDH1A1PARP1
SCHEMBL8425555 0.85 CYP3A4 (0.75) CYP3A4NAMPTXDHALDH1A1PARP1
Silver SCHEMBL11230934 0.85 CYP3A4 (0.75) CYP3A4NAMPTXDHALDH1A1PARP1
Alcohol SCHEMBL28252889 0.85 CYP3A4 (0.65) CYP3A4NAMPTXDHALDH1A1PARP1
Dimethyl Sulfoxide SCHEMBL28289766 0.83 CYP3A4 (0.67) CYP3A4NAMPTXDHALDH1A1PARP1
Dimethylformamide SCHEMBL11127603 0.81 CYP3A4 (0.63) CYP3A4NAMPTXDHALDH1A1PARP1
SCHEMBL7353332 0.80 CYP3A4 (0.55) CYP3A4NAMPTXDHALDH1A1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1113915-A Chemical compounds SMITHKLINE BEECHAM CORP (US) 1995-12-27 CN disclosed