Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | NAMPT | P43490 | 1/20 | 0.71 |
| ▸ | XDH | P47989 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.44 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271340 | 0.95 | CYP3A4 (0.77) | CYP3A4NAMPTXDHALDH1A1PARP1 | |
| SCHEMBL29923659 | 0.95 | CYP3A4 (0.77) | CYP3A4NAMPTXDHALDH1A1PARP1 | |
| Silver SCHEMBL11230934 | 0.93 | CYP3A4 (0.75) | CYP3A4NAMPTXDHALDH1A1PARP1 | |
| SCHEMBL8425555 | 0.93 | CYP3A4 (0.75) | CYP3A4NAMPTXDHALDH1A1PARP1 | |
| Acetic Acid SCHEMBL28050837 | 0.89 | CYP3A4 (0.65) | CYP3A4NAMPTXDHALDH1A1PARP1 | |
| Alcohol SCHEMBL28252889 | 0.89 | CYP3A4 (0.65) | CYP3A4NAMPTXDHALDH1A1PARP1 | |
| Nitric Acid SCHEMBL4907436 | 0.89 | CYP3A4 (0.90) | CYP3A4NAMPTXDHALDH1A1PARP1 | |
| Dimethyl Sulfoxide SCHEMBL28289766 | 0.88 | CYP3A4 (0.67) | CYP3A4NAMPTXDHALDH1A1PARP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL1672747 | 0.87 | CYP3A4 (0.58) | CYP3A4NAMPTXDHALDH1A1PARP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL18169501 | 0.87 | CYP3A4 (0.58) | CYP3A4NAMPTXDHALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115657429-B | Efficient environment-friendly developing solution for PCB and preparation process thereof | 南通赛可特电子有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-115657429-A | Efficient environment-friendly developing solution for PCB and preparation process thereof | 南通赛可特电子有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-112710526-A | Cell fixing and preserving fluid and preparation method and application thereof | 广州江元医疗科技有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-107475663-B | A kind of method of stainless cast steel part salt bath chromizing | 安徽省含山县兴建铸造厂 | 2019-04-23 | — | — | CN | claimed |
| CN-109041839-A | A kind of high viability white willow cuttage and seedling culture method | 阜南县大喜柳编工艺品有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-106833366-B | A kind of ultrahigh-pressure hydraulic cylinder cylinder body | 大大科技(宁国)有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-107474311-B | A kind of preparation method of rubber industry agstone | 张家界荣丰新材料有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-108004765-A | A kind of preparation method of antifouling fishing net | 巢湖市翔宇渔具有限公司 | 2018-05-08 | — | — | CN | claimed |
| CN-107475663-A | A kind of method of stainless cast steel part salt bath chromizing | 安徽省含山县兴建铸造厂 | 2017-12-15 | — | — | CN | claimed |
| CN-106833366-A | A kind of ultrahigh-pressure hydraulic cylinder cylinder body | 大大科技(宁国)有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-102363569-B | Functional calcium carbonate for stone paper | SHANDONG DONGSHENG NEW MAT CO | 2013-03-20 | — | — | CN | claimed |
| CN-102363658-A | Antistatic stone paper for packing | SHANGHAI DONGSHENG NEW MAT CO | 2012-02-29 | — | — | CN | claimed |
| CN-102363569-A | Functional calcium carbonate for stone paper | SHANDONG DONGSHENG NEW MAT CO | 2012-02-29 | — | — | CN | claimed |
| CN-100448351-C | Specimen anti-corrosion stationary liquid | JIANGSU INST OF NUCLEAR MED (CN) | 2009-01-07 | — | — | CN | claimed |
| US-20080089957-A1 | Monocotyledon plant indications extract compositions, method of preparation and pharmaceutical compositions containing them | ACADEMIA SINICA (TW) | 2008-04-17 | — | — | US | claimed |
| CN-101084746-A | Specimen anti-corrosion stationary liquid | JIANGSU INST OF NUCLEAR MED (CN) | 2007-12-12 | — | — | CN | claimed |
| CN-1027716-C | Developing-fixing liquor and developing process for both colour negative film and colour printing paper | LIU SHUBIN (CN) | 1995-02-22 | — | — | CN | claimed |
| CN-1071519-A | High-temp. quick compounding method for colour photographic paper | NO 6 GEOLOGY INVESTIGATION OFF (CN) | 1993-04-28 | — | — | CN | claimed |
| CN-1046395-A | Apparent fixing liquor and developing technique that colour negative and printing paper are general | LIU SHUBIN (CN) | 1990-10-24 | — | — | CN | claimed |
| US-3955983-A | PHENYLENE DIAMINE, 1-PHENYL-3-PYRAZOLIDONE | FUJI PHOTO FILM CO., LTD. (JA) | 1976-05-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080089957-A1 | Monocotyledon plant indications extract compositions, method of preparation and pharmaceutical compositions containing them | OAT, TPMT, NUDT1 | CYP3A4 1370/4885NAMPT 291/4885XDH 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.