Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544559 | 0.86 | CA12 (0.45) | CA12CA9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8117415 | 0.85 | KDM4E (0.51) | CA12CA9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27396577 | 0.84 | CA9 (0.50) | CA12CA9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8661923 | 0.80 | CDK1 (0.43) | CA12CA9ALDH1A1POLBMEN1 | |
| SCHEMBL27408323 | 0.80 | TBXA2R (0.48) | CA12CA9ALDH1A1LMNA | |
| SCHEMBL27426282 | 0.79 | CA12 (0.45) | CA12CA9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8539377 | 0.73 | CA9 (0.60) | CA12CA9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27397751 | 0.72 | CA12 (0.39) | CA12CA9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7933511 | 0.69 | CDK1 (0.63) | ALDH1A1GSTO1LMNAHTTMEN1 | |
| SCHEMBL9201412 | 0.69 | CDK1 (0.43) | CA12CA9ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1087631-A | Novel phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators | HOECHST AG (DE) | 1994-06-08 | — | — | CN | disclosed |