Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137951 | 0.85 | HTT (0.54) | CA9CA12ALDH1A1CYP2C19TSHR | |
| SCHEMBL8537343 | 0.80 | CA1 (0.49) | CA9ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8117415 | 0.75 | KDM4E (0.51) | CA9CA12ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28674936 | 0.75 | CA12 (0.69) | CA9CA12ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8539302 | 0.75 | CA2 (0.71) | CA9CA12ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8827344 | 0.75 | CA1 (0.53) | CA9ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL27396577 | 0.74 | CA9 (0.50) | CA9CA12RIPK1ALDH1A1CYP1A2 | |
| SCHEMBL27417409 | 0.73 | CA12 (0.49) | CA9CA12ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3978111 | 0.73 | CA12 (0.61) | CA9CA12ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8062917 | 0.73 | CA9 (0.74) | CA9CA12ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| EP-0574418-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992013845-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-20 | — | — | WO | disclosed |