SCHEMBL27397751

SCHEMBL27397751

CCCCNS(=O)(=O)c1cc(N(C)C(=S)NC(=O)OCC)ccc1C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.39
CA9 Q16790 4/20 0.39
POLB P06746 1/20 0.37
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
ALDH1A1 P00352 5/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
KDM4E B2RXH2 4/20 0.34
HPGD P15428 2/20 0.34
GAA P10253 2/20 0.34
MAPT P10636 2/20 0.34
HSD17B10 Q99714 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.34
ALOX12 P18054 1/20 0.34
THRB P10828 1/20 0.34
GLA P06280 1/20 0.32
TUBB4A P04350 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8806828 0.87 CA12 (0.38) CA12CA9CA1CA2ALDH1A1
SCHEMBL8803262 0.84 CA2 (0.46) CA12CA9CA1CA2ALDH1A1
SCHEMBL27426282 0.77 CA12 (0.45) CA12CA9POLBALDH1A1CYP1A2
SCHEMBL8117415 0.73 KDM4E (0.51) CA12CA9POLBALDH1A1CYP1A2
SCHEMBL27396577 0.73 CA9 (0.50) CA12CA9POLBCA1CA2
SCHEMBL27417409 0.72 CA12 (0.49) CA12CA9POLBALDH1A1CYP1A2
SCHEMBL8806824 0.71 GAA (0.34) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL27544559 0.70 CA12 (0.45) CA12CA9POLBALDH1A1CYP1A2
SCHEMBL27408323 0.69 TBXA2R (0.48) CA12CA9ALDH1A1LMNA
SCHEMBL8667253 0.66 ALDH1A1 (0.35) POLBALDH1A1CYP3A4CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1087631-A Novel phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators HOECHST AG (DE) 1994-06-08 CN disclosed