Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30975872 | 0.93 | KMT2A (0.32) | KMT2AALDH1A1TSHRGAAHTT | |
| SCHEMBL30975903 | 0.88 | KMT2A (0.36) | KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL30976004 | 0.87 | ALDH1A1 (0.33) | KMT2AALDH1A1TSHRGAAHTT | |
| SCHEMBL30976162 | 0.87 | KMT2A (0.35) | KMT2AALDH1A1TSHRGAAHTT | |
| SCHEMBL30976051 | 0.86 | KMT2A (0.32) | KMT2A | |
| SCHEMBL30975989 | 0.86 | PTGER4 (0.32) | — | |
| SCHEMBL30976018 | 0.86 | ALDH1A1 (0.32) | KMT2AALDH1A1TSHRGAAHTT | |
| SCHEMBL30975865 | 0.85 | PTGER4 (0.30) | — | |
| SCHEMBL30976001 | 0.85 | PTGDR2 (0.31) | — | |
| SCHEMBL30975900 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634159-A1 | SULFOXIMINES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | disclosed |