Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 2/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976017 | 0.94 | ALDH1A1 (0.32) | ALDH1A1TSHRGAAHTTHSD17B10 | |
| SCHEMBL30975972 | 0.92 | ALDH1A1 (0.32) | ALDH1A1TSHRGAAHTTHSD17B10 | |
| SCHEMBL27417593 | 0.87 | KMT2A (0.33) | ALDH1A1TSHRGAAHTTHSD17B10 | |
| SCHEMBL27417567 | 0.85 | ALDH1A1 (0.32) | ALDH1A1TSHRGAAHTTHSD17B10 | |
| SCHEMBL30976018 | 0.85 | ALDH1A1 (0.32) | ALDH1A1TSHRGAAHTTHSD17B10 | |
| SCHEMBL30975872 | 0.85 | KMT2A (0.32) | ALDH1A1TSHRGAAHTTHSD17B10 | |
| SCHEMBL30975819 | 0.85 | PLAT (0.32) | ALDH1A1TSHRGAAHTTHSD17B10 | |
| SCHEMBL30958818 | 0.84 | ALDH1A1 (0.34) | ALDH1A1TSHRGAAHTTHSD17B10 | |
| SCHEMBL30975824 | 0.84 | — | — | |
| SCHEMBL30975971 | 0.84 | PLAT (0.32) | ALDH1A1TSHRGAAHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634159-A1 | SULFOXIMINES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | disclosed |