SCHEMBL27417643

SCHEMBL27417643

CCCn1cnc(CC(C)(C)O)c1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 1/20 0.34
ADORA2A P29274 4/20 0.34
ADORA2B P29275 2/20 0.34
ADORA1 P30542 1/20 0.34
FDPS P14324 1/20 0.33
PDE4A P27815 2/20 0.32
PDE4B Q07343 2/20 0.32
PDE4C Q08493 2/20 0.32
PDE4D Q08499 2/20 0.32
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNE1 P24864 1/20 0.31
CDK2 P24941 1/20 0.31
LMNA P02545 2/20 0.31
CNR2 P34972 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.30
NPC1 O15118 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5655389 0.79 ADORA2A (0.38) ADORA2AADORA2BADORA1PDE4APDE4B
SCHEMBL21554483 0.77 ADORA2A (0.39) GNRHRADORA2AADORA2BADORA1PDE4A
SCHEMBL22670750 0.75 ADORA2A (0.38) GNRHRADORA2AADORA2BADORA1PDE4A
Hydrochloric Acid SCHEMBL5657506 0.74 ADORA2A (0.37) GNRHRADORA2AADORA2BADORA1PDE4A
SCHEMBL20011271 0.70 FDPS (0.44) ADORA2AADORA2BADORA1FDPSPDE4A
SCHEMBL22546477 0.67 ADORA2A (0.40) ADORA2AADORA2BADORA1PDE4APDE4B
SCHEMBL21227159 0.67 CYP2C19 (0.36) ADORA2AADORA2BADORA1CDK1CCNB1
SCHEMBL21227160 0.65 ADORA2A (0.34) ADORA2AADORA2BADORA1
SCHEMBL859472 0.63 ALDH1A1 (0.35) GNRHRADORA2AADORA1FDPSCDK1
SCHEMBL13384141 0.63 ALDH1A1 (0.40) ADORA2AADORA2BADORA1PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024130674-A1 METHOD FOR PREPARING AMPHIPHILIC POLYMER 深圳华大生命科学研究院 2024-06-27 WO disclosed