Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316095 | 0.82 | ELANE (0.35) | TLR8LMNAHPGD | |
| SCHEMBL27518178 | 0.81 | PSMB5 (0.35) | HSD11B1KDM4E | |
| SCHEMBL28286476 | 0.78 | HSD11B1 (0.37) | HSD11B1ADORA3HTR2A | |
| SCHEMBL27635627 | 0.77 | IDO1 (0.36) | TLR8HTR1A | |
| SCHEMBL6266838 | 0.72 | APOBEC3A (0.31) | — | |
| SCHEMBL8461849 | 0.71 | — | — | |
| SCHEMBL5087592 | 0.70 | CFTR (0.33) | TDP1HPGDCFTR | |
| Chlorobenzene SCHEMBL8155712 | 0.69 | TSHR (0.32) | ADORA3 | |
| Chlorobenzene SCHEMBL8156616 | 0.69 | TSHR (0.32) | ADORA3 | |
| Chlorobenzene SCHEMBL9168737 | 0.69 | ADORA3 (0.33) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1112937-A | Metallocene catalyst systems, preparation and use | PHILLIPS PETROLEUM CO (US) | 1995-12-06 | — | — | CN | disclosed |