Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MMP2 | P08253 | 7/20 | 0.42 |
| ▸ | MMP9 | P14780 | 7/20 | 0.42 |
| ▸ | MMP8 | P22894 | 6/20 | 0.42 |
| ▸ | MMP13 | P45452 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27465010 | 0.87 | ATM (0.55) | ATMKMT2AMMP2MMP9MMP8 | |
| SCHEMBL27480105 | 0.87 | MMP2 (0.56) | ATMMMP2MMP9MMP8MMP13 | |
| SCHEMBL4675370 | 0.80 | ATM (0.60) | ATMKMT2AMMP2MMP9MMP8 | |
| SCHEMBL4675367 | 0.80 | ATM (0.60) | ATMKMT2AMMP2MMP9MMP8 | |
| SCHEMBL4671235 | 0.76 | ATM (0.59) | ATMKMT2AMMP2MMP9MMP8 | |
| SCHEMBL4671238 | 0.74 | ATM (0.56) | ATMKMT2AMMP2MMP9MMP8 | |
| SCHEMBL4671232 | 0.74 | ATM (0.56) | ATMKMT2AMMP2MMP9MMP8 | |
| SCHEMBL17559610 | 0.71 | ATM (0.52) | ATMKMT2AMMP2MMP9MMP8 | |
| SCHEMBL17559609 | 0.71 | ATM (0.52) | ATMKMT2AMMP2MMP9MMP8 | |
| SCHEMBL4908095 | 0.66 | ATM (0.47) | ATMKMT2ACA2MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093125-C | Sulfamide-metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-23 | — | — | CN | disclosed |
| CN-1250445-A | Sulfamide-metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2000-04-12 | — | — | CN | disclosed |