Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27419842 | 0.90 | MEN1 (0.46) | KMT2AMEN1 | |
| SCHEMBL27419994 | 0.80 | KDM1A (0.44) | KDM1AMAOBNFKB1NFKB2RELA | |
| SCHEMBL27419818 | 0.76 | GAA (0.48) | KDM1ANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL27419914 | 0.73 | GAA (0.44) | NFKB1NFKB2RELAEPHX2GAA | |
| SCHEMBL27419900 | 0.71 | MEN1 (0.42) | KDM1AMAOBNFKB1NFKB2RELA | |
| SCHEMBL27419889 | 0.71 | MEN1 (0.42) | KDM1AMAOBNFKB1NFKB2RELA | |
| SCHEMBL10802832 | 0.69 | GAA (0.46) | NFKB1NFKB2RELAEPHX2GAA | |
| SCHEMBL10721583 | 0.69 | GAA (0.46) | NFKB1NFKB2RELAEPHX2GAA | |
| SCHEMBL10721576 | 0.69 | GAA (0.46) | NFKB1NFKB2RELAEPHX2GAA | |
| SCHEMBL27419986 | 0.68 | GAA (0.46) | KDM1AMAOBNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092256-A2 | PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-05-02 | — | — | WO | disclosed |