Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 5/20 | 0.34 |
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27419914 | 0.93 | GAA (0.44) | GAANFKB1NFKB2RELAPLG | |
| SCHEMBL27419818 | 0.82 | GAA (0.48) | GAANFKB1NFKB2RELAPLG | |
| SCHEMBL15750409 | 0.79 | BACE1 (0.47) | GAANFKB1NFKB2RELABACE1 | |
| SCHEMBL27419994 | 0.78 | KDM1A (0.44) | NFKB1NFKB2RELAEPHX2KDM1A | |
| SCHEMBL3373246 | 0.77 | GAA (0.34) | GAABACE1 | |
| SCHEMBL7398655 | 0.77 | GAA (0.52) | GAANFKB1NFKB2RELAPLG | |
| SCHEMBL4507930 | 0.77 | GAA (0.47) | GAANFKB1NFKB2RELAPLG | |
| SCHEMBL20904043 | 0.77 | GAA (0.47) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL4517509 | 0.76 | GAA (0.51) | GAANFKB1NFKB2RELAPLG | |
| SCHEMBL15727315 | 0.75 | CTSD (0.53) | GAANFKB1NFKB2RELABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092256-A2 | PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-05-02 | — | — | WO | disclosed |