SCHEMBL27420086

SCHEMBL27420086

CC(C)(C)OC1CC(C(C)(C)C)N(C(=O)C(C)(C)C)C1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ RIPK1 Q13546 1/20 0.30
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19767552 0.75 RIPK1 (0.33) RIPK1LMNA
SCHEMBL28054733 0.74 — —
SCHEMBL19772799 0.71 HCRTR2 (0.33) RIPK1LMNA
SCHEMBL21165814 0.71 NAMPT (0.34) RIPK1
SCHEMBL26556210 0.69 — —
SCHEMBL29163837 0.69 UCHL1 (0.31) —
SCHEMBL16316489 0.68 ATM (0.40) —
SCHEMBL16300658 0.68 ATM (0.40) —
SCHEMBL9603348 0.68 ATM (0.40) LMNA
SCHEMBL9603346 0.68 ATM (0.40) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216526-A1 PREPARATION METHOD FOR DUAL-DRUG-LINKER OF ADC AND USE THEREOF CHENGDU SCIMOUNT PHARMATECH CO., LTD. (CN) 2024-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216526-A1 PREPARATION METHOD FOR DUAL-DRUG-LINKER OF ADC AND USE THEREOF SKP1, ADCY7, ERBB2 RIPK1 296/4885LMNA 1812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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