Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877536 | 1.00 | KMT2A (0.47) | KMT2AMEN1F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5035720 | 0.93 | PRCP (0.48) | KMT2AMEN1F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30313463 | 0.85 | TLR2 (0.47) | KMT2APRCPELANECMA1 | |
| SCHEMBL30309004 | 0.84 | F2 (0.52) | KMT2AMEN1F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4229009 | 0.84 | KMT2A (0.55) | KMT2AMEN1F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4229005 | 0.84 | KMT2A (0.55) | KMT2AMEN1F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL14723747 | 0.84 | NPC1 (0.54) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL10118420 | 0.82 | PRCP (0.52) | KMT2AF2SMN1; SMN2PRCPCYP3A4 | |
| SCHEMBL10118436 | 0.82 | PRCP (0.52) | KMT2AF2SMN1; SMN2PRCPCYP3A4 | |
| SCHEMBL12972648 | 0.82 | FKBP1A (0.51) | KMT2AF2ALDH1A1SMN1; SMN2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137502-A2 | PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-06-27 | — | — | WO | disclosed |