SCHEMBL27420232

SCHEMBL27420232

O=C(NC1C(=O)NC(C(=O)O)CCCCC1c1ccccc1)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FABP7 O15540 1/20 0.43
▸ FABP5 Q01469 1/20 0.43
▸ KMT2A Q03164 2/20 0.41
▸ NAAA Q02083 1/20 0.40
▸ EPHX2 P34913 1/20 0.39
▸ TLR2 O60603 1/20 0.38
▸ TLR1 Q15399 1/20 0.38
▸ MME P08473 3/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27420244 0.90 MMP13 (0.37) FABP7FABP5KMT2ANAAAEPHX2
SCHEMBL27420165 0.88 MMP13 (0.37) FABP7FABP5KMT2AEPHX2TDP1
SCHEMBL27420226 0.86 NAAA (0.50) FABP7FABP5KMT2ANAAAEPHX2
SCHEMBL27421521 0.82 KMT2A (0.39) KMT2ANAAAEPHX2MMETDP1
SCHEMBL27421425 0.80 KMT2A (0.38) FABP7FABP5KMT2AEPHX2TLR2
SCHEMBL27420215 0.79 FABP7 (0.38) FABP7FABP5KMT2AEPHX2TLR2
SCHEMBL27420200 0.79 FABP7 (0.38) FABP7FABP5KMT2AEPHX2TLR2
SCHEMBL27420878 0.79 KMT2A (0.38) FABP7FABP5KMT2ANAAATDP1
SCHEMBL27420809 0.77 KMT2A (0.38) FABP7FABP5KMT2ATDP1
SCHEMBL27420817 0.75 KMT2A (0.42) FABP5KMT2ANAAAEPHX2TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024092256-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-05-02 — — WO disclosed
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