SCHEMBL27420280

SCHEMBL27420280

O=C(Oc1ccccc1)[C@H](Cc1ccccc1)N(O)O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 0.43
PPARA Q07869 7/20 0.43
CYP1A2 P05177 1/20 0.43
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SRR Q9GZT4 2/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41
SLC7A5 Q01650 1/20 0.41
CTRB1 P17538 2/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
ANPEP P15144 1/20 0.40
LAP3 P28838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634682 0.86 SLC7A5 (0.58) PPARGPPARACYP1A2SLC1A3SLC1A2
SCHEMBL7902214 0.84 PPARG (0.41) PPARGPPARACYP1A2SRRSLC1A3
SCHEMBL27472351 0.81 ADRA2B (0.49) ATML3MBTL1ALDH1A1MAPT
SCHEMBL27987428 0.81 CYP1A2 (0.44) CYP1A2SRRSLC1A3SLC1A2SLC1A1
SCHEMBL28878522 0.81 ATM (0.50) ATML3MBTL1CTRB1ALDH1A1MAPT
SCHEMBL5151597 0.81 ATM (0.50) ATML3MBTL1CTRB1ALDH1A1MAPT
SCHEMBL29112710 0.81 CYP1A2 (0.44) PPARGPPARACYP1A2SRRSLC1A3
SCHEMBL28283100 0.81 SRR (0.50) CYP1A2SRRSLC1A3SLC1A2SLC1A1
SCHEMBL29127421 0.80 CYP1A2 (0.43) PPARGPPARACYP1A2SRRSLC1A3
Hydrochloric Acid SCHEMBL28015581 0.80 ATM (0.49) ATMCTRB1ALDH1A1MAPTANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110114348-A The method of keratin material is handled using amide C- glycosides derivatives and contains its cosmetic composition 莱雅公司 2019-08-09 CN disclosed
CN-109219432-A Carboxylated polyphenol derivatives and its beautifying use 欧莱雅 2019-01-15 CN disclosed
CN-103717201-B Use of CB1 receptor antagonists as whitening and/or anti-browning agents for keratin materials L'OREAL (FR) 2015-11-25 CN disclosed
CN-103717201-A Use of CB1 receptor antagonists as whitening and/or anti-browning agents for keratin materials OREAL 2014-04-09 CN disclosed
CN-101744740-B Process for depigmenting keratin materials using dithiolane compounds OREAL 2014-01-08 CN disclosed
CN-101355924-B Use of ceramides for depigmenting the skin OREAL 2012-11-28 CN disclosed
CN-102740829-A Use of a punica granatum extract to fight against the whitening of the hair OREAL 2012-10-17 CN disclosed
CN-101744740-A Process for depigmenting keratin materials using dithiolane compounds OREAL 2010-06-23 CN disclosed
CN-100484509-C Use of C-glycosides for depigmenting skin OREAL (FR) 2009-05-06 CN disclosed
CN-101355924-A Use of ceramides for depigmenting the skin OREAL (FR) 2009-01-28 CN disclosed
CN-1235560-C Use of ascorbic-acid dervative as bleaching agent for beauty REAL O (FR) 2006-01-11 CN disclosed
CN-1507852-A Use of ascorbic-acid dervative as bleaching agent for beauty �ź㴫 2004-06-30 CN disclosed
CN-1138523-C Association of phenol derivatives with extract of iridaceae family for lightening skin and superficial body growth and composition containing same �ź㴫 2004-02-18 CN disclosed
CN-1121850-C Use of unfermented honey as decolouring agent OREAL (FR) 2003-09-24 CN disclosed
CN-1105555-C Use of arbutin monoesters as depigmenting agents OREAL (FR) 2003-04-16 CN disclosed
CN-1404828-A Use of pantethine sulfonic acid and/or its salt as free radical scavenger OREAL (FR) 2003-03-26 CN disclosed
CN-1270801-A Use of unfermented honey as decolouring agent OREAL (FR) 2000-10-25 CN disclosed
CN-1270513-A Use of at least one extract of Chrysanthemum for promoting skin and/or hair pigmentation OREAL (FR) 2000-10-18 CN disclosed
CN-1253495-A Association of phenol derivatives with extract of iridaceae family for lightening skin and superficial body growth and composition containing same OREAL (FR) 2000-05-17 CN disclosed
CN-1208608-A Use of arbutin monoesters as depigmenting agents OREAL (FR) 1999-02-24 CN disclosed