SCHEMBL27423471

SCHEMBL27423471

NC1CCCCC(C(=O)O)NC1=O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 12/20 0.43
▸ ANPEP P15144 3/20 0.43
▸ LNPEP Q9UIQ6 3/20 0.43
▸ ACE P12821 8/20 0.42
▸ ECE1 P42892 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10331846 0.88 ANPEP (0.36) MMEANPEPLNPEPACE
SCHEMBL4078093 0.80 MME (0.35) MMEANPEPLNPEPACEECE1
SCHEMBL10529472 0.79 MME (0.37) MMEACEECE1
SCHEMBL27995821 0.78 CAD (0.43) —
SCHEMBL27995822 0.78 CAD (0.43) —
SCHEMBL7388403 0.77 MME (0.45) MMEACEECE1
SCHEMBL4076122 0.74 CAD (0.35) MMEACEECE1
SCHEMBL6813416 0.72 MME (0.44) MMEACEECE1
SCHEMBL6814128 0.72 MME (0.44) MMEACEECE1
SCHEMBL6501628 0.72 MME (0.44) MMEACEECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024092256-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-05-02 — — WO disclosed
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