SCHEMBL27423478

SCHEMBL27423478

N[C@H]1C(=O)N[C@@H](C(=O)O)CCC[C@@H]1c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 14/20 0.43
▸ ACE P12821 9/20 0.43
▸ ECE1 P42892 1/20 0.39
▸ TP53 P04637 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL7569185 0.70 MEN1 (0.57) TP53L3MBTL1KDM4EMAPTHPGD
SCHEMBL27423471 0.70 MME (0.43) MMEACEECE1
SCHEMBL4522521 0.68 KCNQ3 (0.53) HPGD
SCHEMBL2858904 0.68 MME (0.38) MMEACETP53MAPT
SCHEMBL12592455 0.68 KCNQ3 (0.53) HPGD
SCHEMBL7352068 0.68 KCNQ3 (0.53) HPGD
SCHEMBL7352063 0.68 KCNQ3 (0.53) HPGD
SCHEMBL839092 0.68 KCNQ3 (0.53) HPGD
SCHEMBL31289649 0.67 DPP4 (0.47) TP53L3MBTL1MAPT
SCHEMBL31289648 0.67 DPP4 (0.47) TP53L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024092256-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-05-02 — — WO disclosed
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