Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.38 |
| ▸ | ACE | P12821 | 5/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.34 |
| ▸ | ITGA2 | P17301 | 3/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8801345 | 0.75 | POLB (0.35) | MAPTGAAHSD17B10TP53CYP1A2 | |
| SCHEMBL17675155 | 0.72 | MAPT (0.46) | MMEACEPARP1MAPTGAA | |
| SCHEMBL8585951 | 0.69 | MAPT (0.44) | MAPTHSD17B10LMNATP53CYP1A2 | |
| SCHEMBL27423471 | 0.69 | MME (0.43) | MMEACEANPEPLNPEP | |
| SCHEMBL125094 | 0.69 | MAPT (0.44) | MAPTHSD17B10LMNATP53CYP1A2 | |
| SCHEMBL1252255 | 0.68 | GAA (0.62) | MMEACEPARP1MAPTGAA | |
| SCHEMBL1252254 | 0.68 | GAA (0.62) | MMEACEPARP1MAPTGAA | |
| SCHEMBL2080900 | 0.68 | GAA (0.62) | MMEACEPARP1MAPTGAA | |
| SCHEMBL27423478 | 0.68 | MME (0.43) | MMEACEMAPTTP53 | |
| Phthalimide SCHEMBL28667674 | 0.66 | GSK3B (0.54) | MAPTHSD17B10LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2143728-A1 | Improved process for the preparation of copolymer-1 | Momenta Pharmaceuticals, Inc. (US) | 2010-01-13 | — | — | EP | disclosed |
| EP-2046817-B1 | IMPROVED PROCESS FOR THE PREPARATION OF COPOLYMER-1 | MOMENTA PHARMACEUTICALS INC (US) | 2009-12-16 | — | — | EP | disclosed |
| EP-2046817-A1 | IMPROVED PROCESS FOR THE PREPARATION OF COPOLYMER-1 | Momenta Pharmaceuticals, Inc. (US) | 2009-04-15 | — | — | EP | disclosed |
| US-20080021192-A1 | PROCESS FOR THE PREPARATION OF COPOLYMER-1 | MOMENTA PHARMACEUTICALS, INC. (US) | 2008-01-24 | — | — | US | disclosed |
| WO-2008006026-A1 | IMPROVED PROCESS FOR THE PREPARATION OF COPOLYMER-1 | MOMENTA PHARMACEUTICALS, INC. (US) | 2008-01-10 | — | — | WO | disclosed |