Pyridine

Pyridine

SCHEMBL27424099

c1ccc2c(-c3ncco3)cccc2c1.c1ccncc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.49
ALDH1A1 P00352 7/20 0.49
MAPT P10636 6/20 0.49
HPGD P15428 6/20 0.49
HSD17B10 Q99714 6/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
RAB9A P51151 4/20 0.49
MAPK1 P28482 3/20 0.49
NPC1 O15118 2/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 2/20 0.48
GAA P10253 1/20 0.46
ATM Q13315 2/20 0.45
TSHR P16473 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
BRD4 O60885 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50810 0.92 ALDH1A1 (0.51) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL4431582 0.85 BRD4 (0.48) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL20526076 0.84 MAPT (0.49) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL31241245 0.84 MAPT (0.49) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL26259967 0.83 BRD4 (0.53) KDM4EALDH1A1MAPTHPGDHSD17B10
Pyridine SCHEMBL28166972 0.79 ALDH1A1 (0.50) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL11363800 0.79 BRD4 (0.57) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL4718626 0.78 BRD4 (0.43) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL38656976 0.78 BRD4 (0.47) BRD4PIN1HPGDSLTA4HCYP1A2
SCHEMBL5701217 0.77 MAPT (0.43) KDM4EALDH1A1MAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1110599-C Enzymatic method for textile dyeing NOVOZYMES NORTH AMERICA AS (US) 2003-06-04 CN disclosed
CN-1205755-A Enzymatic process for dyeing textiles NOVO NORDISK BIOCHEM INC (US) 1999-01-20 CN disclosed