Pyridine

Pyridine

SCHEMBL28166972

c1ccc2c(-c3cccc4ccccc34)cccc2c1.c1ccncc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
HPGD P15428 6/20 0.50
KDM4E B2RXH2 5/20 0.50
MAPT P10636 5/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
HSD17B10 Q99714 5/20 0.50
MAPK1 P28482 3/20 0.50
RAB9A P51151 2/20 0.50
NPC1 O15118 2/20 0.50
LMNA P02545 1/20 0.50
TNF P01375 1/20 0.50
NISCH Q9Y2I1 1/20 0.47
TP53 P04637 2/20 0.46
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28202246 0.85 ALDH1A1 (0.56) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2
Phenanthrene SCHEMBL27542935 0.83 ALDH1A1 (0.63) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2
SCHEMBL25302086 0.83 ALDH1A1 (0.59) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2
SCHEMBL27953 0.83 ALDH1A1 (0.59) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2
SCHEMBL29350007 0.83 ALDH1A1 (0.59) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2
SCHEMBL13203236 0.80 TNF (0.63) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2
SCHEMBL30756642 0.80 TNF (0.63) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2
Bromide SCHEMBL8588309 0.80 ALDH1A1 (0.56) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2
SCHEMBL18174178 0.80 ALDH1A1 (0.56) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2
Ammonia Solution, Strong SCHEMBL3156160 0.80 ALDH1A1 (0.56) ALDH1A1HPGDKDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111675649-B Dinaphthalene pyridinium antibacterial material and preparation method and application thereof 山西大学 2021-09-28 CN claimed
CN-111675649-A Dinaphthalene pyridinium antibacterial material and preparation method and application thereof 山西大学 2020-09-18 CN claimed
CN-104829771-B A kind of side chain contains polymer of ring-type azobenzene binaphthyl structure and its production and use 苏州大学 2017-08-01 CN claimed
CN-111675649-B Dinaphthalene pyridinium antibacterial material and preparation method and application thereof 山西大学 2021-09-28 CN disclosed
CN-111675649-A Dinaphthalene pyridinium antibacterial material and preparation method and application thereof 山西大学 2020-09-18 CN disclosed