Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417951 | 0.90 | MAPT (0.42) | MAPTPKMPPM1BPTPN1PPP1CC | |
| SCHEMBL7189528 | 0.90 | MAPT (0.42) | MAPTPKMPPM1BPTPN1PPP1CC | |
| SCHEMBL27550910 | 0.90 | MAPT (0.42) | MAPTPKMPPM1BPTPN1PPP1CC | |
| Acetic Acid SCHEMBL6729875 | 0.89 | MAPT (0.43) | MAPTPKMPPM1BPTPN1PPP1CC | |
| Hydrochloric Acid SCHEMBL4283062 | 0.89 | MAPT (0.44) | MAPTPKMPPM1BPTPN1PPP1CC | |
| Hydrochloric Acid SCHEMBL2920606 | 0.89 | MAPT (0.44) | MAPTPKMPPM1BPTPN1PPP1CC | |
| Trifluoroacetic Acid SCHEMBL8561671 | 0.83 | MAPT (0.39) | MAPTPKMPPM1BPTPN1PPP1CC | |
| SCHEMBL27619781 | 0.80 | MAPT (0.40) | MAPTPKMPPM1BPTPN1KDM4E | |
| SCHEMBL1951212 | 0.79 | PPM1B (0.37) | MAPTPKMPPM1BPTPN1PPP1CC | |
| SCHEMBL27638771 | 0.78 | MAPT (0.35) | MAPTPKMCYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1109057-A | Imidazopyridazine | MERCK PATENT GMBH (DE) | 1995-09-27 | — | — | CN | disclosed |