Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417951 | 1.00 | MAPT (0.42) | MAPTPKMKDM4EHSD17B10CYP1A2 | |
| SCHEMBL7189528 | 1.00 | MAPT (0.42) | MAPTPKMKDM4EHSD17B10CYP1A2 | |
| Hydrochloric Acid SCHEMBL4283062 | 0.98 | MAPT (0.44) | MAPTPKMKDM4EHSD17B10CYP1A2 | |
| Hydrochloric Acid SCHEMBL2920606 | 0.98 | MAPT (0.44) | MAPTPKMKDM4EHSD17B10CYP1A2 | |
| Acetic Acid SCHEMBL6729875 | 0.95 | MAPT (0.43) | MAPTPKMKDM4EHSD17B10CYP1A2 | |
| Chloroacetic Acid SCHEMBL27424329 | 0.90 | MAPT (0.40) | MAPTPKMKDM4EHSD17B10CYP1A2 | |
| SCHEMBL27619781 | 0.89 | MAPT (0.40) | MAPTPKMKDM4EHSD17B10CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL8561671 | 0.89 | MAPT (0.39) | MAPTPKMKDM4EHSD17B10CYP1A2 | |
| SCHEMBL1951212 | 0.87 | PPM1B (0.37) | MAPTPKMPPM1BPTPN1PPP1CC | |
| SCHEMBL22122711 | 0.86 | SOAT1 (0.45) | MAPTPKMKDM4EHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1291892-A | Substituted oxoazaheterocyclyl factor Xa inhibitors | AWENTIS PHARMACEUTICAL INC (US) | 2001-04-18 | — | — | CN | claimed |
| CN-1291892-A | Substituted oxoazaheterocyclyl factor Xa inhibitors | AWENTIS PHARMACEUTICAL INC (US) | 2001-04-18 | — | — | CN | disclosed |