Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14963643 | 0.82 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL5138772 | 0.74 | LMNA (0.44) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL1311882 | 0.74 | LMNA (0.44) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL31130665 | 0.74 | LMNA (0.44) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL3467525 | 0.74 | NAALAD2 (0.43) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL149291 | 0.74 | LMNA (0.38) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL5076638 | 0.72 | LMNA (0.42) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL8764214 | 0.72 | ALDH1A1 (0.54) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL13642563 | 0.72 | CAMK2A (0.46) | LMNAEGLN1ALKBH5SUCNR1TSHR | |
| SCHEMBL28146999 | 0.72 | LMNA (0.42) | LMNAEGLN1ALKBH5SUCNR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1107665-C | Preparation process of 4,4,4-trihalogen butyraldehyde, trihalogen acid and their derivative | GUANGZHOU INST OF CHEMISTRY (CN) | 2003-05-07 | — | — | CN | disclosed |
| CN-1277177-A | Preparation process of 4,4,4-trihalogen butyraldehyde, trihalogen acid and their derivative | GUANGZHOU INST OF CHEMISTRY AC (CN) | 2000-12-20 | — | — | CN | disclosed |