Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980156 | 0.85 | DPP4 (0.68) | DPP4LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL7286165 | 0.85 | DPP4 (0.68) | DPP4LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL522687 | 0.85 | DPP4 (0.68) | DPP4LMNAADRA2AADRA2CHIF1A | |
| Hydrochloric Acid SCHEMBL22713306 | 0.83 | DPP4 (0.65) | DPP4LMNAADRA2AADRA2CHIF1A | |
| Bromide SCHEMBL11538603 | 0.83 | DPP4 (0.65) | DPP4LMNAADRA2AADRA2CHIF1A | |
| Hydrochloric Acid SCHEMBL3753145 | 0.83 | DPP4 (0.65) | DPP4LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL7710838 | 0.82 | DPP4 (0.52) | DPP4LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL8219735 | 0.78 | DPP4 (0.52) | DPP4LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL19649931 | 0.78 | DPP4 (0.52) | DPP4LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL11985509 | 0.76 | LMNA (0.48) | DPP4LMNAADRA2AADRA2CHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090617-C | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| CN-1349796-A | Pyrrole derivatives and medicine composition | NIPPON SHINYAKU CO LTD (JP) | 2002-05-22 | — | — | CN | disclosed |
| CN-1186485-A | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 1998-07-01 | — | — | CN | disclosed |