SCHEMBL522687

SCHEMBL522687

CC(C)C(N)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.68
F2 P00734 1/20 0.52
ADRA2A P08913 1/20 0.52
ADRA2C P18825 1/20 0.52
LMNA P02545 1/20 0.52
HIF1A Q16665 1/20 0.52
KDM4E B2RXH2 1/20 0.52
TAAR1 Q96RJ0 3/20 0.50
ALDH1A1 P00352 1/20 0.50
AOC3 Q16853 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7286165 1.00 DPP4 (0.68) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL1980156 1.00 DPP4 (0.68) DPP4F2ADRA2AADRA2CLMNA
Hydrochloric Acid SCHEMBL22713306 0.97 DPP4 (0.65) DPP4F2ADRA2AADRA2CLMNA
Hydrochloric Acid SCHEMBL3753145 0.97 DPP4 (0.65) DPP4F2ADRA2AADRA2CLMNA
Bromide SCHEMBL11538603 0.97 DPP4 (0.65) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL3271282 0.85 DPP4 (0.45) DPP4ADRA2AADRA2CLMNAHIF1A
SCHEMBL20634768 0.84 DPP4 (0.62) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL77070 0.83 DPP4 (0.68) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL10506371 0.83 DPP4 (0.68) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL3367415 0.83 DPP4 (0.68) DPP4F2ADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119898789-A Flower-like sphere mordenite as well as preparation method and application thereof 中国石油化工股份有限公司 2025-04-29 CN claimed
CN-105939736-B Odor masking amine compositions 阿肯马法国公司 2020-11-06 CN claimed
CN-108250115-B The method of father's younger male cousin's amine coupling synthesizing aryl thioether 成都理工大学 2019-11-08 CN claimed
EP-3102249-B1 ODOUR-MASKED AMINE COMPOSITION ARKEMA FRANCE (FR) 2019-10-16 EP claimed
US-10315982-B2 Odour-masked amine composition ARKEMA FRANCE (FR) 2019-06-11 US claimed
US-20160340292-A1 ODOUR-MASKED AMINE COMPOSITION ARKEMA FRANCE (FR) 2016-11-24 US claimed
WO-2014001075-A1 PROCESS FOR RACEMIZING OPTICALLY ACTIVE ARYLALKYLAMINES BASF SE (DE) 2014-01-03 WO claimed
US-20130345475-A1 PROCESS FOR THE RACEMIZATION OF OPTICALLY ACTIVE ARYLALKYLAMINES BASF SE (DE) 2013-12-26 US claimed
WO-2012037258-A1 PROCESSES FOR PREPARING 1,2-SUBSTITUTED CYCLOPROPYL DERIVATIVES ABBOTT LABORATORIES (US) 2012-03-22 WO claimed
US-20100256126-A1 PIPERIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS HOFFMANN-LA ROCHE, INC. 2010-10-07 US claimed
EP-2032587-A2 ROSUVASTATIN INTERMEDIATES AND PROCESS FOR THE PREPARATION OF ROSUVASTATIN Teva Pharmaceutical Industries Ltd. (IL) 2009-03-11 EP claimed
WO-2008130678-A2 ROSUVASTATIN INTERMEDIATES AND PROCESS FOR THE PREPARATION OF ROSUVASTATIN TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2008-10-30 WO claimed
CN-1225452-C Prepn. of (+)-trans-chrysanthemic acid SUMITOMO CHEMICAL CO (JP) 2005-11-02 CN claimed
US-6310207-B1 MANNICH REACTION CHONG KUN DANG CORP. (KR) 2001-10-30 US claimed
CN-1298862-A Prepn. of (+)-trans-chrysanthemic acid SUMITOMO CHEMICAL CO (JP) 2001-06-13 CN claimed
WO-1999002530-A1 A PROCESS OF MANUFACTURING CAMPTOTHECIN DERIVATIVES CHONG KUN DANG CORP. (KR) 1999-01-21 WO claimed
WO-1996002492-A1 METHOD OF MAKING A BENZYLPROPANAMINE NSP PHARMACEUTICALS, INC. (US) 1996-02-01 WO claimed
EP-0508307-B1 Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound SUMITOMO CHEMICAL CO (JP) 1995-11-29 EP claimed
EP-0508307-A2 Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-10-14 EP claimed
US-4410730-A Process for the production of o-(N-monosubstituted amino)benzyl alcohols SHIONOGI & CO., LTD. (JP) 1983-10-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130345475-A1 PROCESS FOR THE RACEMIZATION OF OPTICALLY ACTIVE ARYLALKYLAMINES HRH1, HNMT, HRH3 DPP4 2210/4885F2 3100/4885ADRA2A 417/4885
US-20160340292-A1 ODOUR-MASKED AMINE COMPOSITION OR51E2, OR10J3, PNMT DPP4 3909/4885F2 3482/4885ADRA2A 140/4885
US-10315982-B2 Odour-masked amine composition OR51E2, OR10J3, CHRM1 DPP4 4000/4885F2 2850/4885ADRA2A 144/4885
US-20100256126-A1 PIPERIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS HTR3A, OPRL1, OPRK1 DPP4 924/4885F2 4840/4885ADRA2A 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.