Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128362 | 0.84 | — | — | |
| SCHEMBL359861 | 0.82 | — | — | |
| Flurothyl SCHEMBL22529162 | 0.76 | CA1 (0.31) | CA1CA2CA9 | |
| SCHEMBL4578813 | 0.72 | — | — | |
| SCHEMBL3302738 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL12445296 | 0.71 | KDM4E (0.34) | CA1CA2CA9 | |
| SCHEMBL11995944 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL11995942 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL11995943 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL18652838 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1115341-C | Novel substituted N-methyl-N- (4- (4- (1H-benzimidazol-2-ylamino) piperidin-1-yl) -2- (aryl) butyl) benzamides for the treatment of allergic diseases | AVENTIS PHARMACEUTICALS CORP (US) | 2003-07-23 | — | — | CN | disclosed |
| CN-1211246-A | Novel substituted N-methyl-N-(4-(1H-benzimidazol-2-yl-amino) piperidin-1-yl)-2-(aryl) butyl) benzamides useful for treatment of allergic diseases | HOECHST MARION ROUSSEL INC (US) | 1999-03-17 | — | — | CN | disclosed |