SCHEMBL12445296

SCHEMBL12445296

CCOCC(F)(F)C(F)(F)COS(C)(=O)=O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MMP9 P14780 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2170402 0.87 USP2 (0.43) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL25135365 0.79 ALDH1A1 (0.32) ALDH1A1
SCHEMBL1981839 0.78 USP2 (0.40) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL27839180 0.76 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL8074146 0.75 CA2 (0.30) CA2
SCHEMBL8075877 0.75 CA2 (0.30) CA2
SCHEMBL14844857 0.72 USP2 (0.43) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL796831 0.72 CA1 (0.56) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL27424965 0.71 CA1 (0.39) CA1CA2CA9
SCHEMBL17466380 0.71 CA1 (0.32) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481774-B2 Method for producing tetrafluoro compound NIPPON SODA CO., LTD. (JP) 2013-07-09 US disclosed
US-20110178323-A1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND NIPPON SODA CO., LTD. (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178323-A1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND F9, CA9, TAF9 KDM4E 2651/4885USP2 4138/4885ALDH1A1 3848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.