Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25480231 | 0.90 | ACHE (0.36) | HRH3 | |
| SCHEMBL12890856 | 0.89 | HRH3 (0.43) | HRH3KCNH2 | |
| SCHEMBL25480233 | 0.87 | HRH3 (0.44) | HRH3KCNH2 | |
| SCHEMBL16192871 | 0.82 | KMT2A (0.31) | — | |
| SCHEMBL23134084 | 0.82 | HRH3 (0.42) | HRH3KCNH2 | |
| SCHEMBL15496526 | 0.82 | NCF1 (0.45) | HRH3 | |
| SCHEMBL408516 | 0.80 | CHRNA7 (0.34) | HRH3KCNH2 | |
| SCHEMBL24671761 | 0.79 | NCF1 (0.46) | HRH3KCNH2 | |
| SCHEMBL8364993 | 0.79 | HRH3 (0.40) | HRH3KCNH2 | |
| SCHEMBL24501875 | 0.79 | HRH3 (0.40) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216513-A1 | FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216513-A1 | FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE | FASN, FABP1, SCD | HRH3 3874/4885KCNH2 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.