SCHEMBL27425847

SCHEMBL27425847

CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC[C@H](CNC(=O)CCCN(C)C)OC(=O)CCCCCCC/C=C\C/C=C\CCCCC

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.58
PRKCE Q02156 1/20 0.58
PRKCQ Q04759 1/20 0.58
PRKCD Q05655 1/20 0.58
SELP P16109 1/20 0.52
CNR2 P34972 2/20 0.50
ALDH1A1 P00352 2/20 0.50
FAAH O00519 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
CNR1 P21554 1/20 0.50
LMNA P02545 1/20 0.50
S1PR1 P21453 1/20 0.49
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8004528 0.97 PRKCA (0.61) PRKCAPRKCEPRKCQPRKCDSELP
SCHEMBL24614919 0.90 PRKCA (0.68) PRKCAPRKCEPRKCQPRKCDSELP
SCHEMBL26122535 0.90 PRKCA (0.68) PRKCAPRKCEPRKCQPRKCDSELP
SCHEMBL27355138 0.90 PRKCA (0.68) PRKCAPRKCEPRKCQPRKCDSELP
SCHEMBL9472418 0.90 PRKCA (0.71) PRKCAPRKCEPRKCQPRKCDSELP
SCHEMBL9472428 0.90 PRKCA (0.71) PRKCAPRKCEPRKCQPRKCDSELP
SCHEMBL9861357 0.90 PRKCA (0.71) PRKCAPRKCEPRKCQPRKCDSELP
SCHEMBL9861368 0.90 PRKCA (0.71) PRKCAPRKCEPRKCQPRKCDSELP
SCHEMBL8017492 0.88 PRKCA (0.60) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL24615031 0.86 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024484-B2 Lipid formulations for gene editing VERVE THERAPEUTICS, INC. (US) 2024-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024484-B2 Lipid formulations for gene editing LIPA, LIPC, ABHD16A PRKCA 1532/4885PRKCE 2129/4885PRKCQ 1274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.