SCHEMBL27426512

SCHEMBL27426512

O=C(O)/C=C/Cc1ccc2cc(O)ccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 2/20 0.41
PTGDR Q13258 2/20 0.41
PTGER4 P35408 2/20 0.41
PTGER2 P43116 2/20 0.41
TBXA2R P21731 1/20 0.41
PTGFR P43088 1/20 0.41
HCAR2 Q8TDS4 3/20 0.41
ALOX5 P09917 3/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
MIF P14174 1/20 0.39
CYP1A2 P05177 1/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
CA12 O43570 1/20 0.38
AKR1B10 O60218 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6214765 0.85 TBXA2R (0.56) PTGER3PTGDRPTGER4PTGER2TBXA2R
SCHEMBL6214767 0.85 TBXA2R (0.56) PTGER3PTGDRPTGER4PTGER2TBXA2R
SCHEMBL1160961 0.82 CA2 (0.50) HCAR2KMT2AESR1ESR2CA12
SCHEMBL3119857 0.82 CA2 (0.50) HCAR2KMT2AESR1ESR2CA12
SCHEMBL1160962 0.82 CA2 (0.50) HCAR2KMT2AESR1ESR2CA12
SCHEMBL28193207 0.79 KDM4E (0.55) ALOX5KMT2AMEN1CYP1A2CA12
SCHEMBL3724651 0.78 CYP1A2 (0.46) HCAR2ALOX5KMT2AMEN1NPC1
SCHEMBL27622370 0.78 PTGER3 (0.65) PTGER3PTGDRPTGER4PTGER2ALOX5
SCHEMBL11366685 0.78 MAOB (0.46) PTGER3PTGER4PTGER2HCAR2CA1
SCHEMBL27622343 0.75 PTGER3 (0.44) PTGER3PTGDRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1109053-C Cross-linkable, photoactive polymer materials ROLIC AG (CH) 2003-05-21 CN disclosed
CN-1151411-A Cross-linkable, photoactive polymer materials ROLIC AG (CH) 1997-06-11 CN disclosed